abstract：OBJECTIVE:To evaluate the ability of epithelial-to-mesenchymal transition-related microRNAs (miRNAs) as serum biomarkers for prognosis and prediction of metastasis in patients with colorectal cancer (CRC). BACKGROUND:Epithelial-to-mesenchymal transition-related miRNAs drive CRC progression and metastasis. However, the...

journal_title：Annals of surgery

authors： Toiyama Y,Hur K,Tanaka K,Inoue Y,Kusunoki M,Boland CR,Goel A

更新日期：2014-04-01 00:00:00

abstract：OBJECTIVE:To perform a systematic review of economic evaluations of enhanced recovery pathways (ERP) for colorectal surgery. BACKGROUND:Although there is extensive literature investigating the clinical effectiveness of ERP, little is known regarding its cost-effectiveness. METHODS:A systematic literature search ident...

journal_title：Annals of surgery

authors： Lee L,Li C,Landry T,Latimer E,Carli F,Fried GM,Feldman LS

更新日期：2014-04-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to investigate whether individualized deliberate practice on a virtual reality (VR) simulator results in improved technical performance in the operating room. BACKGROUND:Training on VR simulators has been shown to improve technical performance in the operating room (OR). Current...

journal_title：Annals of surgery

authors： Palter VN,Grantcharov TP

更新日期：2014-03-01 00:00:00

abstract：OBJECTIVE:To evaluate the influence of preoperative dysplasia grade, appearance, and site on risk and location of cancer in patients with colitis. BACKGROUND:The ability to predict the presence and location of cancer in colitis patients with dysplasia is essential to facilitate recommendations regarding the necessity ...

journal_title：Annals of surgery

authors： Kiran RP,Ahmed Ali U,Nisar PJ,Khoury W,Gu J,Shen B,Remzi FH,Hammel JP,Lavery IC,Fazio VW,Goldblum JR

更新日期：2014-02-01 00:00:00

abstract：OBJECTIVE:To assess the feasibility of developing a simulated ward environment in which to assess the ward-based care of surgical patients by clinicians of varying levels of experience (construct validation). BACKGROUND:Increasing evidence points to the importance of the postoperative or ward-based phase of surgical c...

journal_title：Annals of surgery

authors： Pucher PH,Aggarwal R,Srisatkunam T,Darzi A

更新日期：2014-02-01 00:00:00

abstract：OBJECTIVE:The outcome of pelvic exenteration was compared in patients with locally advanced primary (LAP) cancer and recurrent rectal cancer (RRC). BACKGROUND:There are few reports comparing the results of pelvic exenteration for primary advanced rectal cancer and RRC. METHODS:Consecutive patients undergoing pelvic e...

journal_title：Annals of surgery

authors： Bhangu A,Ali SM,Brown G,Nicholls RJ,Tekkis P

更新日期：2014-02-01 00:00:00

abstract：OBJECTIVE:To determine the impact of length of stay upon 30-day outcomes. BACKGROUND:It has been recommended the goal length of stay (LOS) after laparoscopic Roux-en-Y gastric bypass (LRYGB) should be 1 day to improve resource utilization. This study's aim was to assess LRYGB outcomes by LOS. METHODS:Data were obtain...

journal_title：Annals of surgery

authors： Morton JM,Winegar D,Blackstone R,Wolfe B

更新日期：2014-02-01 00:00:00

abstract：OBJECTIVE:To determine the proportion of registered trials published in the surgical literature, to compare, in registered trials, the primary outcomes registered with those published and to determine whether outcome-reporting bias favored significant primary outcomes. BACKGROUND:Trial protocol registration before pat...

journal_title：Annals of surgery

authors： Killeen S,Sourallous P,Hunter IA,Hartley JE,Grady HL

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVE:To examine preoperative dietary influences on gut-associated lymphoid tissue (GALT) cell number in the context of postoperative infectious complications. BACKGROUND:There is little clinical evidence regarding whether nutritional routes affect GALT size and/or phenotype. The influence of GALT atrophy on clini...

journal_title：Annals of surgery

authors： Okamoto K,Fukatsu K,Hashiguchi Y,Ueno H,Shinto E,Moriya T,Saitoh D,Yamamoto J,Hase K

更新日期：2013-12-01 00:00:00

abstract：OBJECTIVE:Comparison of short- and long-term effects after laparoscopic Heller myotomy (LHM) and endoscopic balloon dilation (EBD) considering the need for retreatment. BACKGROUND:Previously published studies have indicated that LHM is the most effective treatment for Achalasia. In contrast to that a recent randomized...

journal_title：Annals of surgery

authors： Schoenberg MB,Marx S,Kersten JF,Rösch T,Belle S,Kähler G,Vassiliou MC,Lüth S,von Renteln D

更新日期：2013-12-01 00:00:00

abstract：OBJECTIVES:The aim of this systematic review was to assess the impact of surgical safety checklists on the quality of teamwork and communication in the operating room (OR). BACKGROUND:Safety checklists have been shown to impact positively on patient morbidity and mortality following surgery, but it is unclear whether ...

journal_title：Annals of surgery

authors： Russ S,Rout S,Sevdalis N,Moorthy K,Darzi A,Vincent C

更新日期：2013-12-01 00:00:00

abstract：OBJECTIVE:To perform a systematic review and meta-analysis of studies comparing operative to nonoperative therapy in adult FC patients. Outcomes were duration of mechanical ventilation (DMV), intensive care unit length of stay (ICULOS), hospital length of stay (HLOS), mortality, incidence of pneumonia, and tracheostomy...

journal_title：Annals of surgery

authors： Leinicke JA,Elmore L,Freeman BD,Colditz GA

更新日期：2013-12-01 00:00:00

abstract：OBJECTIVE:To assess existing measures of pathologic response to neoadjuvant therapy in esophageal and junctional cancer, and to recommend an optimum classification. BACKGROUND:Multimodal therapy is increasingly the standard of care for locally advanced esophageal cancer. Numerous measures of pathologic response have b...

journal_title：Annals of surgery

authors： Donohoe CL,O'Farrell NJ,Grant T,King S,Clarke L,Muldoon C,Reynolds JV

更新日期：2013-11-01 00:00:00

abstract：OBJECTIVES:To assess the impact of varying approaches to congenital diaphragmatic hernia (CDH) repair timing on survival and need for ECMO when controlled for anatomic and physiologic disease severity in a large consecutive series of patients with CDH. BACKGROUND:Our publication of 60 consecutive patients with CDH in ...

journal_title：Annals of surgery

authors： Kays DW,Islam S,Larson SD,Perkins J,Talbert JL

更新日期：2013-10-01 00:00:00

abstract：OBJECTIVE:To compare cancer-specific results of local excision with major resection. BACKGROUND:Technological advances have enabled endoscopic and local excision techniques to be applied in the treatment of early colorectal cancer in preference to radical surgery. METHOD:Patients with stage 0 (carcinoma in situ) or s...

journal_title：Annals of surgery

authors： Bhangu A,Brown G,Nicholls RJ,Wong J,Darzi A,Tekkis P

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Computer-assisted robotic surgery allows complex resections and anastomotic reconstructions to be performed with nearly identical standards to open surgery. We applied this technology to a variety of pancreatic resections to assess the safety, feasibility, versatility, and reliability of this ...

journal_title：Annals of surgery

authors： Zureikat AH,Moser AJ,Boone BA,Bartlett DL,Zenati M,Zeh HJ 3rd

更新日期：2013-10-01 00:00:00

abstract：OBJECTIVE:"The elderly" is an often used but poorly defined descriptor of surgical patients. Investigators have used varying subjectively determined age cutoffs to report outcomes in the elderly. We set out to use objective outcomes data to determine the "at-risk" elderly population. METHODS: PATIENTS:129,331 patient...

journal_title：Annals of surgery

authors： Kurian AA,Wang L,Grunkemeier G,Bhayani NH,Swanström LL

更新日期：2013-09-01 00:00:00

abstract：OBJECTIVE:Comparative effectiveness research has mostly been focused on comparison of treatment techniques. The goal of the present study was to extend the research to physician specialty. BACKGROUND:Both surgeons and interventionalists (cardiologists and radiologists) are involved in endovascular repairs (EVAR) of ao...

journal_title：Annals of surgery

authors： McCutcheon BA,Talamini MA,Chang DC,Rose JA,Bandyk DF,Wilson SE

更新日期：2013-09-01 00:00:00

abstract：OBJECTIVE:To construct a postoperative nomogram to estimate the risk of local recurrence for patients with desmoid tumors. BACKGROUND:The standard management of desmoid tumors is resection, but many recur locally. Other options include observation or novel chemotherapeutics, but little guidance exists on selecting tre...

journal_title：Annals of surgery

authors： Crago AM,Denton B,Salas S,Dufresne A,Mezhir JJ,Hameed M,Gonen M,Singer S,Brennan MF

更新日期：2013-08-01 00:00:00

abstract：UNLABELLED:By linking surgeon surveys to the National Cancer Database, we found that surgeons' tendency to perform more extensive thyroid resection is associated with greater use of radioactive iodine for stage I thyroid cancer. OBJECTIVE:To determine the relationships between surgeon recommendations for extent of res...

journal_title：Annals of surgery

authors： Haymart MR,Banerjee M,Yang D,Stewart AK,Doherty GM,Koenig RJ,Griggs JJ

更新日期：2013-08-01 00:00:00

abstract：OBJECTIVE:We hypothesized that training to expert-derived levels of speed and motion will lead to improved learning and will translate to better operating room (OR) performance of novices than training to goals of speed or motion alone. BACKGROUND:Motion tracking has been suggested to be a more sensitive performance m...

journal_title：Annals of surgery

authors： Stefanidis D,Yonce TC,Korndorffer JR Jr,Phillips R,Coker A

更新日期：2013-07-01 00:00:00

abstract：PURPOSE:Though histological grade is known to have a major prognostic impact in metastatic mucinous appendiceal adenocarcinomas, the prognostic impact of grade in localized disease, and the validity of the American Joint Committee on Cancer AJCC Staging Manual 7th edition's decision to combine moderately and poorly dif...

journal_title：Annals of surgery

authors： Overman MJ,Fournier K,Hu CY,Eng C,Taggart M,Royal R,Mansfield P,Chang GJ

更新日期：2013-06-01 00:00:00

abstract：BACKGROUND:Gastrectomy remains a major operation with potential for significant deterioration in patients' health-related quality of life (QOL). This study assessed differences in QOL among patients after distal (DG), proximal (PG), or total (TG) gastrectomy. METHODS:We prospectively enrolled patients undergoing gastr...

journal_title：Annals of surgery

authors： Karanicolas PJ,Graham D,Gönen M,Strong VE,Brennan MF,Coit DG

更新日期：2013-06-01 00:00:00

abstract：OBJECTIVE:To develop a model for the identification of individuals at risk for carotid stenosis (CS) that could be useful in a clinical setting when trying to decide whether screening is worthwhile. BACKGROUND:Evidence that aggressive medical therapy and life style changes reduce the risk of stroke in individuals with...

journal_title：Annals of surgery

authors： Greco G,Egorova NN,Moskowitz AJ,Gelijns AC,Kent KC,Manganaro AJ,Zwolak RM,Riles TS

更新日期：2013-06-01 00:00:00

abstract：OBJECTIVE:Our objective was to evaluate the safety and durability of biologic mesh for single-staged reconstruction of contaminated fields. INTRODUCTION:The presence of contamination during ventral hernia repair (VHR) poses a significant challenge. Some advocate for a multistaged reconstructive approach with delayed d...

journal_title：Annals of surgery

authors： Rosen MJ,Krpata DM,Ermlich B,Blatnik JA

更新日期：2013-06-01 00:00:00

abstract：OBJECTIVE:To determine whether increasing distance between helicopter ambulance airbase and either home residence or referring facility is associated with an increased risk of injury-related mortality. BACKGROUND:A dramatic increase in the absolute number and utilization of Helicopter Emergency Medical Services transp...

journal_title：Annals of surgery

authors： Rhinehart ZJ,Guyette FX,Sperry JL,Forsythe RM,Murdock A,Alarcon LH,Peitzman AB,Rosengart MR

更新日期：2013-06-01 00:00:00

abstract：OBJECTIVE:To evaluate discrepancies between trial registry entries and final reports of randomized controlled trials (RCTs) published in major general surgical journals. BACKGROUND:Health care decisions are based on published results in peer-reviewed journals. Mandatory trial registration was introduced to increase tr...

journal_title：Annals of surgery

authors： Rosenthal R,Dwan K

更新日期：2013-06-01 00:00:00

abstract：BACKGROUND:Although a randomized trial demonstrated a survival benefit of cytoreductive surgery (CRS) and intraperitoneal chemotherapy (IPC) over systemic chemotherapy alone, the treatment of peritoneal carcinomatosis from colorectal cancer (CRPC) is still a matter of debate. The aims of this study were to evaluate lon...

journal_title：Annals of surgery

authors： Goéré D,Malka D,Tzanis D,Gava V,Boige V,Eveno C,Maggiori L,Dumont F,Ducreux M,Elias D

更新日期：2013-06-01 00:00:00

abstract：OBJECTIVE:We aimed to determine whether the severity of inhalation injury evokes an immune response measurable at the systemic level and to further characterize the balance of systemic pro- and anti-inflammation early after burn and inhalation injury. BACKGROUND:Previously, we reported that the pulmonary inflammatory ...

journal_title：Annals of surgery

authors： Davis CS,Janus SE,Mosier MJ,Carter SR,Gibbs JT,Ramirez L,Gamelli RL,Kovacs EJ

更新日期：2013-06-01 00:00:00

abstract：OBJECTIVE:To determine the factors that may predict music-induced relaxation in friends and family of patients in the emergency department. BACKGROUND:It remains unclear to date which demographic and experiential factors predict the effectiveness of music-induced relaxation. Furthermore, in-hospital stressors for frie...

journal_title：Annals of surgery

authors： Tilt AC,Werner PD,Brown DF,Alam HB,Warshaw AL,Parry BA,Jazbar B,Booker A,Stangenberg L,Fricchione GL,Benson H,Lillemoe KD,Conrad C

更新日期：2013-05-01 00:00:00

abstract：OBJECTIVE:The objective of this pilot study was to investigate the potential for long-term overall survival (OS) after liver transplantation for colorectal liver metastases (CLMs). BACKGROUND:Patients with nonresectable CLMs have poor prognosis, and few survive beyond 5 years. CLMs are currently considered an absolute...

journal_title：Annals of surgery

authors： Hagness M,Foss A,Line PD,Scholz T,Jørgensen PF,Fosby B,Boberg KM,Mathisen O,Gladhaug IP,Egge TS,Solberg S,Hausken J,Dueland S

更新日期：2013-05-01 00:00:00

abstract：OBJECTIVE:The aim of this study is to identify a set of microRNAs (miRNAs) as prognostic molecular biomarkers for the progression of Barrett esophagus (BE) to esophageal adenocarcinoma (EAC) to rationalize the surveillance programs in patients with BE. BACKGROUND:Histological dysplasia is currently used as the main bi...

journal_title：Annals of surgery

authors： Revilla-Nuin B,Parrilla P,Lozano JJ,de Haro LF,Ortiz A,Martínez C,Munitiz V,de Angulo DR,Bermejo J,Molina J,Cayuela ML,Yélamos J

更新日期：2013-05-01 00:00:00

abstract：BACKGROUND:Controversy exists on the use of mesh in the repair of paraesophageal hernias (PEH). This debate centers around the type of mesh used, its value in preventing recurrence, its short- and long-term complications, and the consequences of those complications compared with primary repair. Decision analysis is a m...

journal_title：Annals of surgery

authors： Obeid NM,Velanovich V

更新日期：2013-04-01 00:00:00

abstract：OBJECTIVE:This investigation aimed at exploring the prospects of a cure for persistent medullary thyroid cancer (MTC) stratified by basal calcitonin levels before reoperation and the number of lymph node metastases previously removed at outside facilities. BACKGROUND:There is no evidence-based information supporting t...

journal_title：Annals of surgery

authors： Machens A,Dralle H

更新日期：2013-04-01 00:00:00

abstract：OBJECTIVE:To evaluate the effect of laparoscopic sleeve gastrectomy (LSG) on fasting and meal-stimulated release of the gut hormones ghrelin, pancreatic polypeptide (PP), peptide-YY (PYY), glucagon-like peptide-1 (GLP-1), and amylin and of the adipocytokine leptin. BACKGROUND:Mounting evidence suggests that the mechan...

journal_title：Annals of surgery

authors： Dimitriadis E,Daskalakis M,Kampa M,Peppe A,Papadakis JA,Melissas J

更新日期：2013-04-01 00:00:00

abstract：OBJECTIVE:Minimally invasive techniques have expanded the donor pool for living kidney donation. We changed our approach to single-port donor nephrectomy in 2009 and have compared outcomes with traditional multiple-port laparoscopic donor nephrectomy. BACKGROUND:The development of minimally invasive surgical technique...

journal_title：Annals of surgery

authors： Barth RN,Phelan MW,Goldschen L,Munivenkatappa RB,Jacobs SC,Bartlett ST,Philosophe B

更新日期：2013-03-01 00:00:00

abstract：OBJECTIVE:To determine the incidence of Wnt pathway activation in patients with stage I NSCLC and its influence on lung cancer recurrence. BACKGROUND:Despite resection, the 5-year recurrence with localized stage I nonsmall cell lung cancer (NSCLC) is 18.4%-24%. Aberrant Wnt signaling activation plays an important role...

journal_title：Annals of surgery

authors： Shapiro M,Akiri G,Chin C,Wisnivesky JP,Beasley MB,Weiser TS,Swanson SJ,Aaronson SA

更新日期：2013-03-01 00:00:00

abstract：OBJECTIVES:To develop, validate, and implement a competency assessment tool (CAT) for technical surgical performance in the context of a summative assessment process for the National Training Programme in Laparoscopic Colorectal Surgery (NTP). BACKGROUND:The NTP is an educational initiative by the National Cancer Acti...

journal_title：Annals of surgery

authors： Miskovic D,Ni M,Wyles SM,Kennedy RH,Francis NK,Parvaiz A,Cunningham C,Rockall TA,Gudgeon AM,Coleman MG,Hanna GB,National Training Programme in Laparoscopic Colorectal Surgery in England.

更新日期：2013-03-01 00:00:00

abstract：OBJECTIVE:To validate the global features of postoperative adverse outcomes for surgical patients with schizophrenia. BACKGROUND:Patients with schizophrenia were known to have a higher risk of complications during hospitalization. Quality of care has become the key factor in reducing their potential mortality afterwar...

journal_title：Annals of surgery

authors： Liao CC,Shen WW,Chang CC,Chang H,Chen TL

更新日期：2013-03-01 00:00:00

abstract：OBJECTIVE:To investigate whether the accuracy of magnetic resonance imaging (MRI) after neoadjuvant systemic therapy (NST) is affected by molecular features of primary breast cancer and the use of human epidermal growth factor receptor 2 (HER2)-targeted agents. BACKGROUND:Improved understanding of factors affecting th...

journal_title：Annals of surgery

authors： Moon HG,Han W,Ahn SK,Cho N,Moon WK,Im SA,Park IA,Noh DY

更新日期：2013-01-01 00:00:00